Simplecart.js is a very minimalist e-commerce tool that I have wanted to play round with for ages. Nor didn’t have huge requirements and Drupal commerce or Übercart would certainly have been overkill both in terms of time needed to set up and in the complexity of management.
I had a thoroughly enjoyable time working with simplecart.js. The documentation was accessible and had plenty of cut and paste-able axamples and the code just worked. Drupal was a bit more of a faff, as ever. I think that simplecart.js would work particularly well for people who are running a single page shop on a statically generated blog or something of that nature.